N2 C elegans [evIS82B] N2 [unc129p::gfp+dpy-20]
Cheminformatics approaches for metabolomics research - Tobias Kind (UC Davis Genome Center) Metabolomics is part of the modern life sciences tree including genomics, transcriptomics and proteomics. One of the major goals in metabolomics is to identify small molecules including lipids, organic acids, sugars and amino acid and to obtain spatial and temporal snapshots of metabolite concentrations from complex biological matrices. The results are used to obtain greater insight into plant and animal metabolism and to understand complex cellular processes. Cheminformatics approaches play a crucial role in metabolomics because properties of organic molecules can be modeled in-silico and are matched against experimentally obtained result from ***ytical techniques including liquid chromatography-mass spectrometry (LC-MS) and gas chromatography-mass spectrometry (GC-MS). The accuracy of such predictions including octanol water partition coefficients (logP), acid dissociation constants (pKa) and boiling points (bp) are important to reduce the search space from millions of possible structural isomers down to a low number of potential candidate structures. Besides that, cheminformatics software tools must be able to handle millions of structures and a multitude of structure formats and should provide simple-to-use graphical front ends for novice users and versatile command line parameters for experts. We used Marvin GUI components including ChemAxon MarvinView, Standardizer and Reactor as well as the JAVA API components in a metabolomics environment to generate molecular ...
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Solar Fan and Coolers by Tantra International Mumbai [www.homedecor- to KV Aromatics Private LimitedManufacturer, Exporter & Supplier of Menthol Crystals, Oil and Finished ProductsThe company was established in 2005 as a private limited company. Strict adherance to internationalquality standards & well equipped quality testing laboratoryare some of the key feature of ourorganization.We are well known in the market for oru customized solution, Timely delivery schedule & Ability tosupply bulk quantities.Our product list includes Mint Products, Natural Essential Oils & Aroma Fine Chemicals.We offer premium grade Menthol Powder, Liquid Menthol, Mentha & Peppermint Oils.Our Alpha & Beta Pinene-95 are a class apart.We are specialzied in offering Natural Essential Oils.Linalool & Geraniol are some of our best selling products.Octanol, Limonene, Cis-3-Hexenol & Hexenyl Acetate are some of our Aroma Fine Chemicals. For more details, log on at:
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Pressing and Shearing Machine by Ameet Machine Tools Manufacturing Co. New Delhi [ to KV Aromatics Private LimitedManufacturer, Exporter & Supplier of Menthol Crystals, Oil and Finished ProductsThe company was established in 2005 as a private limited company. Strict adherance to internationalquality standards & well equipped quality testing laboratoryare some of the key feature of ourorganization.We are well known in the market for oru customized solution, Timely delivery schedule & Ability tosupply bulk quantities.Our product list includes Mint Products, Natural Essential Oils & Aroma Fine Chemicals.We offer premium grade Menthol Powder, Liquid Menthol, Mentha & Peppermint Oils.Our Alpha & Beta Pinene-95 are a class apart.We are specialzied in offering Natural Essential Oils.Linalool & Geraniol are some of our best selling products.Octanol, Limonene, Cis-3-Hexenol & Hexenyl Acetate are some of our Aroma Fine Chemicals. For more details, log on at:
Marvinsketch: Free Alternative to Chemsketch for Mac An application for drawing molecules, reactions and so on. Can do almost the same as Chemsketch on Windows.
Protein Crystallization Protein Crystallization. Concept: Supersaturate solution long enough to nucleate one crystal, then lower supersaturation to prevent further nucleation and allow one crystal to grow slowly. Protein: lysozyme. Well diameter: 400 microns. Temperature quench profile: Initial temperature while filling: 20C. Nucleation temperature: 4C for 30mins. Growth temperature: 16C. Oil: FC-43, Surfactant: 12% Tridecafluoro-1-Octanol, Aqueous: Lysozyme 75 mg/ml, 0.05M NaAc, pH 4.5 0.5M NaCl
Drop Storage without stabilizing surfactant Storage without a stabilizing surfactant. This storage method uses wells adjacent to, but connected to the flow channel. The drops flow by the wells when moving at high flow rates if the well is shallow in depth, comparable with the height of the flow channel. When the flow stops the drops spontaneously dock into the nearest well in a game of microfluidic musical chairs. In this method the first drop docks into the last well and the last drop docks into the first well. Without surfactant to stabilize the drop some mixing of drops occurs and typically the contents of about three or four adjacent drops are shared. In this movie a fluorinated oil (FC-43, 3M) mixed with a surfactant (12%w/w, Tridecafluoro octanol, Sigma-Aldrich) was used. The surfactant lowers surface tension making it easy to create drops and simultaneously slows coalescence of drops. Extraction of the drops from the wells is possible when the flow direction is reversed, making recovery of the droplets possible. The movie is recorded in real time. www.brandeis.edu www.brandeis.edu
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Calorimetric determination of Enthalpy of Combustion. From 20to9.com Early experimental effort at providing home tuition in chemistry via YouTube. Please visit 20to9.com for later efforts using a better video camera. A simple calorimetric approach is used to determine the molar enthalpy change of combustion of methanol. This videoclip looks at the practical details and the mathematical calculations used to get joules from temperature change. 0.6g of methanol (CH3OH) is burned - causing the temperature of 100g of water (specific heat capacity 4.2J/g/K) to rise by 20 celcius. The enthalpy change is determined to be -420 kJ/mol. This value will be lower than expected due to heat losses to the surroundings. Apologies for the poor quality of the video and the very basic form of presentation used. If it's a topic that's causing you difficulties, perhaps it will be of some help. Rgds FS
HOW DOES A MOSQUITO TRAP WORK What makes the mosquito traps so effective. Watch this movie from Triwood1973 to learn more.
Structure of 3-(bromomethyl)-4-octanol Using the Ace Organic web-based program the structure of 3-(bromomethyl)-4-octanol is drawn in the Marvin Sketch software.
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