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  • Pemphigus Vulgaris Dr. Wendy Levinbook, MD discusses Pemphigus Vulgaris. See more at PLEASE RATE AND COMMENT!!! Pemphigus vulgaris (PV) is the most common form of pemphigus in North America and Europe. The mean age of onset is 50 to 60 years of age and it affects both ***es equally. It is more common in Jews and in people of Mediterranean descent. Clinically, mucous membranes are always involved. Patients typically present with painful oral mucous membrane erosions although other mucous membranes such as the pharynx, larynx, esophagus, conjunctiva, ***, penis, vagina, and labia may be involved. Cutaneous involvement is variable. The primary lesion is a non-inflamed, flaccid bullae. However, intact bullae are found infrequently because the vesicle roof consists of only a thin portion of epidermis that breaks easily. Therefore, the most common mucocutaneous lesions are erosions subsequent to ruptured bullae. These lesions are typically painful, not pruritic and they are often large, due to their tendency to spread peripherally. Lesions are positive for Nikolsky's sign (lateral pressure of unblistered skin at the periphery of active lesions causes the epidermis to shear off) and for Asboe Hansen's sign (pressure to the top of a bullae causes extension of the blister to adjacent unblistered skin). PV is an intraepidermal autoimmune blistering disorder that occurs secondary to the formation of antibodies that interact with desmoglein 3. This is a 130 kDa transmembrane ...
  • Flesh Grinder - Chronic Mucocutaneous Candidiasis Brazilian Goregrind. From the album SPLATTER
  • Kawasaki Disease kawasaki disease found in young Japenese children about one though two years of age and the mortality rate is about one percent being fatal. The discovers are Dr. Howard, Kushner, Dr.Christina, Turner, Dr.Jarec C. Burns, Dr.John F. Baston, Mr.Robert Macnee, and named after the first physician who disocovered the disease, condition causes inflammation in the walls of small- and medium- sized arteries throughout the body, including the coronay arteries, which supply blood to the heart muscle also called mucocutaneous lymph node syndrome because it also affects lymph nodes,skin, and the mucous membranes inside the mouth, nose and throat.There are also red eyes,body rash, swollen, red lips and tongue, swollen red feet and hands all these were general symptoms of this disease.
  • ENDOSCOPIC (NON-SURGICAL) REMOVAL OF MULTIPLE LARGE TUMORS F ENDOSCOPIC (NON-SURGICAL) REMOVAL OF MULTIPLE LARGE TUMORS FROM STOMACH IN A PATIENT WITH PEUTZ-JEGHERS SYNDROME PEUTZ-JEGHERS SYNDROME: Peutz-Jeghers syndrome (PJS) is a familial syndrome consisting of mucocutaneous pigmentation, gastrointestinal polyposis and cancers of gut & other sites like breast, ovary, and testes. PJS has an autosomal dominant inheritance with variable and incomplete penetrance. Germline mutations of STK11/LKB1 gene on 19p cause this syndrome. Mucocutaneous pigmentation may be noted in early infancy. These deposits of melanin are most commonly found around the mouth, nose, lips, buccal mucosa, hands, and feet, and may also be present in peri*** and genital areas. PJS polyps may be found in stomach, small intestine, or colon, but they tend to be prominent in the small intestine. These polyps may increase in size and cause small intestinal obstruction or intussusceptions that may occur in early infancy. Acute upper gastrointestinal bleeding and chronic faecal blood may complicate the disease. PATIENT: The patient was a 25 yr male who had mucocutaneous pigmentation and multiple polyps in the stomach and duodenum. He presented with bleeding from gastric polyps. As the polyps in stomach were numerous, (more than 20 in number) and were large in size (some equal to small egg size), he had been advised to undergo surgery. Surgery planned was total gastrectomy. PROCEDURE: The patient underwent video-endoscopy of the esophagus, stomach and ...