AP Biology: DNA Transcription and Translation Watch more free lectures and examples of AP Biology at Other subjects include Geometry, Algebra 1/2, Pre Calculus, Pre Algebra, Calculus, Statistics, Chemistry, Physics, and Computer Science. -All lectures are broken down by individual topics -No more wasted time -Just search and jump directly to the answer
explaining dmd mutations In my video explaining dmd last year, i only mention nonsense mutations, you might have thought all dmd's are caused by this. That is not the case, in this video i explain other causes in my own terms, including nonsense, missense mutations and a brief venture into frameshift mutations. This is unscientific in its approach, in as easy terms as i could manage. Parts may be incorrect because im not a genetic expert, please forgive any errors. I hope it helps, there is much more info out there on the internet, please explore and learn about this terminal disease, any questions please ask in the comments below. Thank you, Ian
Understanding SIFT Scores SIFT (sift-) is a bioinformatics algorithm for predicting whether an amino acid substitution affects protein function. SIFT is typically used for prediction of nonsynonymous variants. This tutorial explains the SIFT scores (obtained from the SIFT website) in more detail.
A neonatal encephalopathy with seizures in standard poodle dogs with a missense mutation in the can From the Springer article: A neonatal encephalopathy with seizures in standard poodle dogs with a missense mutation in the canine ortholog of ATF2 by: Chen, Xuhua; Johnson, Gary S.; Schnabel, Robert D.; Taylor, Jeremy F.; Johnson, Gayle C.; Parker, Heidi G.; Patterson, Edward E.; Katz, Martin L.; Awano, Tomoyuki; Khan, Shahwanaz; O'Brien, Dennis P.; Video clip of a seizure in a 4-week-old standard poodle with neonatal encephalopathy with seizures (NEWS). The seizure has focal onset with facial twitching, lip smacking, and myoclonic jerking of the head. It then generalizes to vocalization and clonic limb movements and ends with tonic extension of the limbs. There was a postictal period (not shown) of agitation and disorientation. Journal: Neurogenetics Vol. 9 Issue 1 DOI: 10.1007/s10048-007-0112-2 Published: 2008-01-22
Jamiroquai love foolosophy live Torino (part.1) Great!!!!!!!!
Missense Mutations.flv understanding of biochemistry, missense mutation frameshif a base DNA pair resulting mutant codon and mutan polipeptide when transcription and translation. finally forming mutant polypeptide
Webinar: Genome-Wide Association Studies: Hunting for Genes in the New Millennium November 20, 2008. Teri Manolio, MD, Ph.D., director of the Office of Population Genomics reported the latest on GWAS results and talked about genomics and health. More: www.genome.gov
59. Mutations 1 of 5 This video looks at mutations - the source of genetic variability.
mutations, mutagens and repairs mutations include: missense - different AA nonsense - stop codon silent - no change neutral - no different protein function splicing - intron not removed Frameshift - insertion or deletion Inverstions - can be due to transposons Mutagens: radiation virus aflotoxin transposons repair Proofread Mismatch SOS Light repair Excision Oxidizing
Jamiroquai love foolosophy live Torino (part.2)
DNA single point mutations Video to show the different types of single point DNA mutations and their ultimate affect on amino acids.
Silent Mutations Clouds Race across the sky, silently conversations of nature evolve around us ....
Course Overview and Introduction: The Biologic Basis for ***ysis of Genetic Variants Thomas Pearson, MD, Ph.D. Professor, University of Rochester School of Medicine. Genetics for Epidemiologists: Applications of Human Genomics to Population Sciences, was a short course for investigators and trainees in the field of epidemiology and related population-based sciences. It was conducted by the National Human Genome Research Institute (NHGRI) on May 13-14, 2008 at Northwestern University in Chicago. The goal of Genetics for Epidemiologists (GFE) was to familiarize epidemiologists and population-based researchers with recent developments in the theory and methods of human genetics that might be applied to the study of the distribution, natural history and etiology of diseases in populations. The course consisted of eight one-hour lectures and focused on the interface between genetics and epidemiology. Emphasis was on the application of modern human genome ***ysis methodologies to studies of human populations through the design, conduct, ***ysis, and interpretation of studies which effectively answer the epidemiologic question of interest. GFE is co-sponsored by the Office of Population Genomics, NHGRI, and the Department of Preventive Medicine at Northwestern University's Feinberg School of Medicine. These videocasts are provided as an educational tool for epidemiologic investigators interested in learning more about applying genomics to their work. More: www.genome.gov
DNAmutations.avi DNA mutations, Missense, Nonsense, Silent, Frameshift
What Causes OCD This is my very brief explanation of what causes OCD. Here are my sources: BBC. (2010). BBC - Science & Nature - Human Body and Mind - Root of obsession. Retrieved from Maloney, B. (2009). Saving Sammy. NY, New York: Crown Publishers. Myers, D. (2010). Psychology. (rev. 9th ed.). NY, New York: Worth Publishers. WebMD. (2010). Obsessive-Compulsive Disorder (OCD) Causes, Symptoms, Treatments and More. Retrieved from compulsive-disorder-ocd-topic-overview. Mell, LK, Davis, L & Owens, D. (2005). Association between streptococcal infection and obsessive-compulsive disorder, Tourette's syndrome, and tic disorder. Pediatrics 116.1, 56-61. 0-.library.pcc.edu &contentSet=IAC- Documents&type=retrieve&tabID=T002&prodId=AONE&docId= A134312060&source=gale&srcprod=AONE&userGroupName=pcc&version=1.0. Retrieved from Academic OneFile. Ozaki, N., Goldman, D., Kaye, WH, Plotinicov, K., Greenbag, BD, Lappalaine, J., Rudnick, G., & Murphy, DL (2003). Serotonin transporter missense mutation associated with a complex neuropsychiatric phenotype. Molecular Psychiatry, 8, 933-936. Retrieved from Academic OneFile. Pallanti, S., Bernardi, S., Antonini, N., Singh, N., & Hollander, E. (2009). Ondansetron augmentation in treatment-resistant obsessive-compulsive disorder: a preliminary, single-blind, prospective study. CNS Drugs, 23.12, 1047-1056. Retrieved from Academic OneFile. ScienceDaily. (2009). Strep Throat Does Not Appear To Cause OCD ...
DNA mutations frameshift Video to describe how frameshift mutations work in DNA.
Juicy Protein Synthesis Ye, this song is dedicated to all my bio peeps livin' in the struggle, introducing, g-baby, elavrize and youngwoo, It's all good baby-baby. [David] It started with a gene, That wanted to be a protein, yeah, that was always, its dream. Through transcription and translation, We'll teach this lesson to the biology nation. Step one, the fun has begun, In the nucleus is where it's all done. RNA P-3 makes a complimentary, Strand, yeah this stuff ain't so bland. That's initiation, with elongation, Next is the last step called termination. So RNA P-3 reaches UAG or UAA or UGA And stops to copy - that's the end of transcription. That's in the bio textbook, its not fiction. 5 prime cap and Poly-A tail, Added to the mRNA so it ain't frail Splisosomes excise, introns so it's nice, Leaving the exons, I'm Dave, I like rice. You know very well, what it is, Protein synthesis x2 It had a goal, and it reached it, And now you know, it's a protein. [Garrett] Now its why we've all been waitin', Cause its time for protein translation! Out of the nucleus into the cyto, Now ribosomes bind, all the time yo. They consist of two subunits, That bind to mRNA when it permits, Moves in 5 to 3 directions, Deciphering codons in triplet collections. tRNA brings all the right aminos, Cause its anticodons always knows. MET is the one to start, Attaches to the P site and does its part. The next lil' T foes to the A site, And MET attaches with all its might. Lil T's continue to the A, Creating a chain, going ...