
Phalanx or Traitor? Impact of Gut Microbial Communities on Insect Health Air date: Thursday, March 01, 2012, 3:00:00 PM Timedisplayed is Eastern Time, Washington DC Local Category: Wednesday Afternoon Lectures Description: Research in the Handelsman lab focuses on understanding diversity in microbial communities and the role of microbial communities in infectious disease. In particular, we are interested in understanding a gut community that serves as a source of opportunistic pathogens, and the soil microbial community as a source of new genes and proteins. To study opportunistic pathogens, we developed a model system with the normal gut microbiota in lepidopteran insects. These normally benign bacteria kill the host under certain conditions, and our work aims to determine the mechanistic basis for host death. To explore microbial diversity, we use functional metagenomics to probe genetic and biochemical diversity in microbial communities. Metagenomics circumvents culturing, thereby capturing genetic information from organisms that cannot be cultured by standard methods, which represent the majority of the microbial world. Through this approach, we have discovered novel antibiotics and antibiotic resistance genes, some of which encode bifunctional proteins. The NIH Wednesday Afternoon Lecture Series includes weekly scientific talks by some of the top researchers in the biomedical sciences worldwide. For more information, visit: The NIH Director's Wednesday Afternoon Lecture Series Author: Dr. Jo Handelsman, Yale University Runtime: 01:13:33 ...

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Rewinding the limb story Dr. Miguel Torres, from the CNIC, Madrid, explains the results arising from the Science article "Diffusible signals, not autonomous mechanisms determine the main proximodistal limb subdivision"

Mitochondria: dynamic organelles critical for human health Mitochondria: dynamic organelles critical for human health Air date: Wednesday, October 03, 2012, 3:00:00 PM Description: Mitochondria are dynamic organelles that fuse, divide, and move. Human genetic studies indicate that these processes are important for normal functioning of tissues, particularly neurons. Mutations in Mitofusion-2 (Mfn2) cause peripheral neuropathy (Charcot-Marie-Tooth 2A), and mutations in optic atrophy 1 (OPA1) cause eye disease (dominant optic atrophy). Mouse knockout studies focused on the mitofusins Mfn1 and Mfn2 have shown that mitochondrial fusion is important for organellar function. Dr. Chan will discuss mouse studies that reveal the physiological functions of mitochondrial dynamics. In addition, Dr. Chan will discuss how new mouse models can be combined with imaging approaches to understand the role of mitochondrial dynamics in neurodegeneration. The NIH Director's Wednesday Afternoon Lecture Series, colloquially known as WALS, is the highest-profile lecture program at the NIH. Lectures occur on most Wednesdays from September through June from 3:00 to 4:00 pm in Masur Auditorium, Building 10 on the NIH Bethesda campus. Each season includes some of the biggest names in biomedical and behavioral research. The goal of the WALS is to keep NIH researchers abreast of the latest and most important research in the Unites States and beyond. An added treat is the annual J. Edward Rall Cultural Lecture, which features top authors and other cultural ...

Fusions in Zoom zoom into a previous simulation to watch some early fusions in more detail. Internal food levels are colorcoded [numerical values are arbitrary]. In the background image, the red channel is solid food, which cannot be taken up by the mycelial network. The blue channel is diffusible and communication means of the mycelium, it also solves the solid red pixels into the green diffusible food, which is absorbed by the mycelium

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Symptoms of Acute Bacterial Prostatitis Part 2 Prostate gland seems to be a small gland in the bodies of men, it affect lots of ***ual function of men. Symptoms of acute bacterial prostatitis can be very obvious, and they vary in different kinds of infection. In clinical cases, there are two types of symptoms of prostatitis: local symptoms and systemic symptoms. Patients who have hematogenous infection have systemic symptoms and for those who have lymphatic or diffusible infection, they are more possible to have local symptoms. Prostatitis is a common disease occur on male and the average age of the patients are getting younger. So what are the symptoms of acute bacterial prostatitis? Local symptpms: Irritation in the bladder and urethra: frequent urinate, urgent urinate, pain when urinate, urinate difficulty, hematuresis and even urodialysis. Irritation in the rectum: pain in the *** and perineum, constipation, pain when discharge and the pain sometimes spread to the abdomen. Systemic symptoms: A sudden hit of symptoms, high fever, pain and atony in the muscle and articulation, inappentence, vomit, and even symptoms of toxaemia.

Membrane Tension Maintains a United Front Using his own neutrophils, Orion Weiner demonstrates how physical forces and not diffusible factors ensure that migrating cells have a single leading edge.

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How To Exercise With A Disc Bulge Neuromuscular therapist Sam Visnic from shows you exercises for disc bulges.

SIGA Majpell 5 - Roof renovation from the outside The all-purpose, easy to apply vapour control layer Majpell covers not less than three different applications: between and above-rafter insulation and roof renovation from the outside. In combination with the approved SIGA high-performance adhesives Majpell provides for permanently airtight building envelopes for roof, wall and ceiling structures in the interior. With a fixed sd value of 5m Majpell is on the one hand particularly diffusible. On the other hand it provides utmost safety, because it protects the building against excessive moisture penetration in the construction phase, for example by fresh cast plaster floor or walls just plastered. Thus Majpell can substitute variable vapour control layers which otherwise are mainly used for roof renovation. Combining Majpell with the breathable membrane Majcoat (sd value = 0.1 m) ensures perfect moisture transportation with a diffusion gradient of 50:1. www.siga.ch

Buller's Eye spore starts to grow on some solid food, which it can't directly absorb, so it gives off a substance (which is invisible in this video and blue in some of my older ones) that can dissolve the environment into a diffusible state, which now can be absorbed. The invisible substance that every hypha emits into the environment is actually avoided (as good as possible) by the growing tips themselves. Later, another type of hypha emerges, that seeks to fuse with other parts of the mycelium, thus decentralizing the network, as now there are multiple paths to other places inside the net. This in turn adds robustness to the system, as a single link breakage wouldn't disconnect large parts of the network. Now all i need is a little recycling..

Hydrogen Diffusion Demonstration Demonstration that shows the diffusion of hydrogen from welds made using different types of electrodes. Also shows the beneficial effect of preheating and slow cooling and the importance of proper care of low-hydrogen electrodes. Production was jointly funded by DNV Columbus and Spectra Energy. Animation was provided by BMT Fleet Technology.

How Arc Welding Works Basic 1.5 min talk on how it works, taken from a larger film which was used to educate GE employees on how to weld correctly. Irving Langmuir from General Electric invented atomic hydrogen welding. the video has diagrams and animation to help show the basics on how metals are annealed

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CONCENTRATION OF SOLUTIONS; PART 5; PLASMA COLLOID OSMOTIC PRESSURE by Professor Fink.wmv Professor Fink explains the Plasma Colloid Osmotic Pressure. In this lecture, Professor Fink shows how the total solute concentration of a fluid (in milliosmoles per L) can be used to calculate its osmotic pressure of a fluid. Since Blood Plasma contains non-diffusible proteins, it is slightly hypertonic compared to other body fluids, giving it an osmotic pressure of about 25 mm Hg higher than other fluids.

Buller's Eye (Zoom) spore starts to grow on some solid food, which it can't directly absorb, so it gives off a substance (which is invisible in this video and blue in some of my older ones) that can dissolve the environment into a diffusible state, which now can be absorbed. The invisible substance that every hypha emits into the environment is actually avoided (as good as possible) by the growing tips themselves. Later, another type of hypha emerges, that seeks to fuse with other parts of the mycelium, thus decentralizing the network, as now there are multiple paths to other places inside the net. This in turn adds robustness to the system, as a single link breakage wouldn't disconnect large parts of the network. Now all i need is a little recycling..

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IRP Scientific Imaging Webinar (Part 3) - Clare Waterman, NIH "Applying New Imaging Techniques to Your Research: Advice from the Experts" (Part 3) The resolution of light microscopy was long thought to be limited by the wavelength of light, but recent advances have far surpassed this barrier and the most recent technologies are now allowing for the super-resolution imaging of biomolecules at a subcellular level, including visualizing membrane glycoproteins, observing physical interactions between proteins, and studying cellular processes in 3-D. This webinar will explore how some of the latest technologies can be applied and implemented to advance your research. Our expert panel from the National Institutes of Health Intramural Research Program will: • Share their experiences using cutting-edge microscopy technologies • Discuss the advantages, challenges, and limitations of current systems • Provide advice on how you can best apply these technologies Clare Waterman, Ph.D., is a Senior Investigator in the Intramural Research Program at the NIH. She leads the Laboratory of Cell and Tissue Morphodynamics at the National Heart, Lung, and Blood Institute. For more about Dr. Waterman's research, visit intramural.nhlbi.nih.gov

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Enzymes: A Simple Way To Improve Your Health Part 6 Digestive Enzymes (Hydrolases) Digestive enzymes provide relief for the digestive system because they break down proteins. There action is especially beneficial for those who have digestive conditions such as IBS, Ulcerative Colitis, Celiac Disease, and Gluten Sensitivity. The human digestive system has 4 major sites of digestion: the oral cavity, the stomach, the duodenum, and the jejunum. Digestive enzymes are naturally secreted by different glands: the salivary glands, the glands in the stomach, the pancreas, and the glands in the small intestine. When foods are consumed, they must be broken down into simple, soluble, and diffusible substances before they can be absorbed into the body. Digestive enzymes start their action in the oral cavity by using saliva to break down food starches into smaller molecules. The various digestive enzymes help to break down the different components of foods such as starches, proteins, fatty acids, and sugars. Digestive enzyme supplements are becoming more popular as more people are learning that they have food allergies and digestive conditions. Most, but not all, digestive enzymes in supplements are extracted from natural foods. Although digestive enzyme supplements are available, the best way to obtain them is to eat natural foods that contain them. Raw fruits, vegetables, and "live food" juices are excellent sources of enzymes. There are three classes of ...

Alzheimers:Toll of Beta-Amyloid And Tau Tangles Alzheimers Is the accumulation of amyloid-beta plaque deposits and protein tau tangles in the brain. It kills over 75000 people in the US each year. As many as 13.2 million people will have the disease in the US by 2050. AD inflicts the worst kind of devastation, with the loss of bodily functions, ultimately leading to death. An adult brain has 100 billion nerve cells, or neurons with extensions connected at 100 trillion points called synapses, where information flows. In AD, information transfer at synapses begins to fail as their number declines. An estimated 5.4 million Americans have Alzheimers disease. Most are elderly. One in eight people over 65 have the disease. The annual cost to the nation is 83 billion. The non-economic cost of AD care to family members can't be tolled. As the mean age of the worlds population increased, dementia has also increased. Its estimated that over 24 million people live with a form of dementia today. With 4.6 million new cases every year. The disease is extremely complicated with several proteins involved in its cause and progression. Cholesterol and inflammation are part of the disease process. Strokes and head injuries make Alzheimers more likely, they cause inflammation of the brain Genetic Causes of AD A po E4: The lipid transport apolipoprotein E4 is the largest genetic risk factor that leads to excessive amyloid beta plaque buildup and late-onset A D. Learning and memory dysfunction are caused by the loss of GABAergic inter ...

Flashpoint Season 4 Episode 7 - Shockwave Two bombs are set off while Sam, Spike and Raff are responding to a Hot Call at an office building, trapping them and nine civilians inside with a third seemingly non-diffusible bomb. They soon realize that the answers to their questions, as well as the bomb's creator, are closer then they think. Flashpoint s04e07 Flashpoint S4e7 s04e7 S4e7 4x7 Season 4 episode 7 tv shows S4 s04 se4 e7 ep7 4x7 4 S04 E7 HQ episodes serie series watch online complete full tv television hd hq part 1 part 2 part 3 part 4. Watch full Flashpoint Season 4 Episode 7 Shockwave watch Flashpoint Season 4 Episode 7 Shockwave full episode online watch Flashpoint Season 4 Episode 7 Shockwave for free watch Flashpoint Season 4 Episode 7 Shockwave free online watch Flashpoint Season 4 Episode 7 Shockwave full episode watch Flashpoint Season 4 Episode 7 Shockwave watch online watch Flashpoint Season 4 Episode 7 Shockwave full free.

SIGA Majpell 5 - The vapour control layer for roof, wall and ceiling structures The all-purpose, easy to apply vapour control layer Majpell covers not less than three different applications: between and above-rafter insulation and roof renovation from the outside. In combination with the approved SIGA high-performance adhesives Majpell provides for permanently airtight building envelopes for roof, wall and ceiling structures in the interior. With a fixed sd value of 5m Majpell is on the one hand particularly diffusible. On the other hand it provides utmost safety, because it protects the building against excessive moisture penetration in the construction phase, for example by fresh cast plaster floor or walls just plastered. Thus Majpell can substitute variable vapour control layers which otherwise are mainly used for roof renovation. Combining Majpell with the breathable membrane Majcoat (sd value = 0.1 m) ensures perfect moisture transportation with a diffusion gradient of 50:1. www.siga.ch

The Role of Hydrogen in the Welding of Steel Silent film from the 1950's that explains the role of diffusible hydrogen in welding of steel. From Delft University of Technology in the Netherlands.