
PROJECT4AWESOME: Lupus Foundation Copyright To "Lupus Foundation of America": "Lupus is a chronic, autoimmune disease that can damage any part of the body (skin, joints, and/or organs inside the body). Chronic means that the signs and symptoms tend to last longer than six weeks and often for many years. In lupus, something goes wrong with your immune system, which is the part of the body that fights off viruses, bacteria, and germs ("foreign invaders," like the flu). Normally our immune system produces proteins called antibodies that protect the body from these invaders. Autoimmune means your immune system cannot tell the difference between these foreign invaders and your body's healthy tissues ("auto" means "self") and creates autoantibodies that attack and destroy healthy tissue. These autoantibodies cause inflammation, pain, and damage in various parts of the body." Help those in need this year by donating any extra holiday spending cash to a local Lupus charity, or to the Lupus Foundation of America. Help those who cannot fully experience this holiday season by giving them a shimmer of hope. Visit and hit "donate" to make any contribution that you possibly can. Any amount can help. Thanks for the watch, and thanks for donating. And thank you Project4Awesome!

HGSI Exclusive with CEO Mario Marciano on Benlysta for Lupus Drug Rare Video Footage Exclusive Interview CEO Mario Marciano Stock Market Mastermind! http (HGSI) Human Genome Sciences Benlysta Drug Approval for Lupus Patients. New Break through in Human Genome Sciences Benlysta drug approval for lupus patients. Will the Benlysta FDA Approval Come? We believe so at SMF and we will cover the pros and the cons of the HGSI new drug and benefits to humanity. We will take a look at one of the most positive developments in "biotechnology" in the past 50 years. We have highlighted HGSI and the longer term trends relative to the current drug developments. BENLYSTA is an investigational human monoclonal antibody drug. It is the first in a new class of drugs called BLyS-specific inhibitors that recognize and inhibit the biological activity of B-lymphocyte stimulator, or BLyS, which was discovered by HGS in 1996. We and GlaxoSmithKline (GSK) are developing BENLYSTA under a co-development and commercialization agreement entered into in 2006. In lupus, rheumatoid arthritis and certain other autoimmune diseases, elevated levels of BLyS are believed to contribute to the production of autoantibodies -- antibodies that attack and destroy the body's own healthy tissues. BENLYSTA has successfully met its primary endpoint in two pivotal Phase 3 trials in seropositive patients with systemic lupus erythematosus (SLE). In June 2010, HGS and GSK submitted regulatory applications seeking approval to market BENLYSTA in the ...

Her Diamonds - Rob Thomas (Cover) - Junkyard Academy You'll notice by the intro that I mention this link; Please help people like Marisol Thomas, (Rob Thomas' wife), who are stricken with this rare disease. What is Lupus? Lupus is a chronic, autoimmune disease that can damage any part of the body. "Autoimmune" means your immune system cannot tell the difference between these foreign invaders and your body's healthy tissues and creates autoantibodies that attack and destroy healthy tissue. It's painful and quite a nasty disease and those who get diagnosed usually don't live too long after being diagnosed. (Typically 5 years). You can imagine how much of a kink it puts on your lifestyle, not to mention your life. Rob states in an July 2009 interview on "Life in the Autoimmune Lane" website; There's an incredible amount of sadness that comes with something like that. There are moments where I think I flirted with a thinner personal line than Ive ever done before, but, really, I'm writing a song about how people deal with hard times, and that hard time is universal, that hard time can be anything. So, please, do what you can, send your good thoughts and vibes their way and, Rob, we're behind you. It touched home here in the Junkyard, because my wife almost lost ME three times to Kidney failure. I am posting this song as a dedication to Noelle, my wife who save my life and donated a kidney to me. I can't imagine the myriad of feelings she experienced at the prospect of loosing me after just getting me back. I ...

Dermatitis Herpetiformis Dr. Wendy Levinbook, MD discusses Dermatitis Herpetiformis. See more at PLEASE RATE AND COMMENT!!! Dermatitis herpetiformis (DH) may occur at any age but patients typically present in the 2nd to 4th decades of life. It is twice as common in males. Most patients have an associated asymptomatic gluten sensitive enteropathy that may be demonstrated by small bowel biopsy. Clinically, patients present with single or grouped vesicles, papules, or urticarial plaques. Lesions are typically distributed symmetrically on extensor surfaces with involvement of the elbows, knees, buttocks, shoulders, and sacral areas most commonly. Many also have involvement of the scalp, posterior nuchal area, face, and facial hairline. Mucous membranes are typically spared. Patients usually experience severe burning and itching. These symptoms often precede the appearance of skin lesions by 8 to 12 hours. In addition, signs and symptoms such as steatorrhea, abnormal D-xylose absorption, iron or folate deficiency anemia due to malabsorption, achlorhydira, atrophic gastritis, and pernicious anemia as a result of gluten sensitive enteropathy may occur. On electron microscopic exam, blister formation is in the lamina lucida. Histopathologic exam is characterized by collections of neutrophils in the dermal papillae forming microabscesses. Eosinophils and dermal edema leading to subepidermal separation are also typically present. Direct immunofluorescence of normal appearing or perilesional ...

The Future of Early Cancer Detection Watch Professor John Robertson discuss the future of cancer detection, featuring Early CDT-Lung, a blood test, covered by Medicare and private insurance, currently being used in the US to aid in the risk assessment of lung cancer, before symptoms start appearing. For more information, visit ?utm_campaign=The-Future-of-Early-Cancer-Detection-Oct.2010&utm_source=YouTube Additional information, about lung cancer, lung cancer symptoms, risk assessment and other lung cancer related topics can be found at .

The Antibodies Song This song is to help us remember autoantibodies and the autoimmune diseases they cause. It is inspired by Wakko Warner's The 50 States and their capitals song. Lyrics: The Antibodies Song ANA and Anti-Smith are for Lupus Rheumatoid Factor Rheumatoid arthritis Theres anti-centromere if youre looking for CREST Double stranded DNA is Lupus nephritis Anti-SSA and anti-SSB are the antibodies for Sjogrens Disease Anti-RNP for MCTD Anti-basement membrane is for Goodpastures disease Anti-jo 1 for polymyositis ANCA can be found in microscopic polyarteritis Anti-GAD diabetes mellitus And Anti smooth muscles in autoimmune hepatitis Anti-mitochondrial PBC In Celiac sprue look for Anti-TTG Anti-histone drug induced SLE in Scleroderma youll find SCL 70 Lets say that a patient has a PE Youll want to send Anti cardiolipin antibody As long as youre working up a hypercoagulable state Send Lupus anticoagulant and APLA, mate TSI is in Graves disease Now lets say your patient has a high MCV Pernicious anemia it may be Send Anti-parietal cell Ab Anti TPO Hashimotos thyroiditis Acetylcholine receptor Myasthenia gravis Finally Antiplatelet antibody Is not needed to diagnose ITP Thats all the antibodies for now

Effectively Treat Rheumatoid Arthritis with Natural Medicine by Dr. Angela Agrios, ND - Naturopathic Doctor Angela Agrios (Pacific Palisades, CA) explains how Naturopathic Medicine is able to reverse Rheumatoid Arthritis.

Dr Ye Qian pt 1 2010 JC Bystryn Pemphigus & Pemphigoid Meeting: From the Bench to the Bedside November 5-6, 2010 in Bethesda MD V gene repertoire in pemphigus foliaceus autoantibodies A copy of the slides can be found at

Pemphigus Foliaceus and Pemphigus Erythematosus Dr. Wendy Levinbook, MD discusses Pemphigus Foliaceus and Pemphigus Erythematosus. See more at PLEASE RATE AND COMMENT!!! Pemphigus foliaceus (PF) has several subsets including an endemic form (fogo selvagem) and pemphigus erythematosus (PE, also known as Senear-Usher Syndrome). All have similar clinical and immunopathologic features. Idiopathic PF and PE are rare disorders seen predominantly in the elderly. Men and women are affected equally. The endemic form of PF is seen in rural areas of Brazil and typically occurs in children and in young adults without any racial or ethnic predilection. Clinically, the primary lesion common to all is a superficial, flaccid, vesiculopustule, which ruptures, leading to the formation of scaly, crusted erosions. Lesions are typically painful and patients often describe a burning sensation. In PF and endemic PF, disease may be localized to seborrheic areas such as the face, scalp or upper trunk or it may generalize resulting in an exfoliative erythroderma. PE is the localized form of PF and represents a clinical overlap between PF and cutaneous lupus. Patients present with red, scaly, crusted lesions usually limited to the upper back, neck and head. Facial plaques may have a malar distribution similar to systemic lupus erythematosus. This form may generalize into a picture indistinguishable from that of PF. In all types, mucosal surfaces are not affected and exposure to sun and heat may exacerbate symptoms. PF, endemic PF ...

Lung Cancer Blood Test - EarlyCDT-Lung Physician Testimonials Pt. 3 Hear from leading physicians across the United States who have used EarlyCDT-lung as an aid for early lung cancer detection and risk assessment of patients at high risk for lung cancer. For more information, visit ?utm_campaign=Physician-Testimonials-Pt.-3&utm_source=YouTube Additional information on lung cancer symptoms, lung cancer awareness, lung cancer early detection, and risk assessment for lung cancer can be found at . Find lung cancer before symptoms appear.

Lung Cancer Blood Test - EarlyCDT-Lung Physician Testimonials Pt. 2 Hear from physicians who have used EarlyCDT-lung as an aid for early lung cancer detection and risk assessment of patients at high risk for lung cancer. For more information, visit ?utm_campaign=Physician-Testimonials-Pt.-2&utm_source=YouTube Additional information on lung cancer symptoms, lung cancer awareness, early detection of lung cancer, and lung cancer risk assessment can be found at .

Dr Aimee Payne pt 2 2010 JC Bystryn Pemphigus & Pemphigoid Meeting: From the Bench to the Bedside November 5-6, 2010 in Bethesda MD Review of autoantibodies against all known non-desmoglein antigens in pemphigus A copy of the slides can be found at

Dr Aimee Payne pt 1 2010 JC Bystryn Pemphigus & Pemphigoid Meeting: From the Bench to the Bedside November 5-6, 2010 in Bethesda MD Review of autoantibodies against all known non-desmoglein antigens in pemphigus A copy of the slides can be found at

Highlights from the Ninth International Congress on Lupus Dr. Gary Gilkeson is Vice Chairman of the Department of Medicine for Research at the Medical University of South Carolina. He also serves as Chair of the Lupus Foundation of America Medical-Scientific Advisory Council. In this video, Dr. Gilkeson highlights some of the important new research findings that were presented during the Ninth International Congress on Lupus that was held in June 2010 in Vancouver, British Columbia, Canada. Dr. Gilkeson summarizes the status of efforts to develop new, safe, more tolerable, and effective treatments for lupus, recent achievements in research to identify the genes that contribute to lupus, and studies examining the role of interferon in triggering lupus disease activity. Dr. Gilkeson also reviews emerging evidence on the importance of Vitamin D for people with lupus, and the increasing recognition of the role other parts of the immune system play in causing lupus.

Perspectives on B-cell Research in Lupus The immune system is made up of many different cells, each with a specific role to play. In lupus, the immune system is out of balance causing the immune system to produce autoantibodies, antibodies that are directed to the body's own tissue. The question for lupus researchers is why these autoantibodies are present and why they are are targeting 'self.' Dr. Gregg Silverman is Head of the Laboratory of B-cell Immunology at the University of California, San Diego. He and his lab have been studying B-cells and how they contribute to the development of lupus. In this video he discusses his work and offers insight on the current status and future direction of lupus research.

Cicatricial Pemphigoid Dr. Wendy Levinbook, MD discusses Cicatricial Pemphigoid. See more at PLEASE RATE AND COMMENT!!! Cicatricial pemphigoid (CP) is a rare blistering disease characterized by erosive lesions of the mucous membranes and skin that result in scarring. The mean age of onset is in the early 60's and there is a slight female predominance. There is no known racial or geographic clustering. Other names for this disorder include benign mucous membrane pemphigoid, desquamative gingivitis, and ocular pemphigus. Clinically, oral and conjunctival mucous membranes are most frequently affected and are typically the first sites of involvement. In the mouth, the gingiva, buccal mucosa, and palate are typically involved and patients may present with mucosal erosions or tense blisters. Adhesions may develop in severe disease and gingival involvement can result in loss of teeth. Ocular involvement typically manifests as unilateral or bilateral conjunctivitis or as burning, dryness, or foreign body sensation. Severe disease can lead to scarring and vision loss. Other mucosal sites that may be affected include the nasopharyngeal, laryngeal, esophageal, genital, and rectal mucosa. Cutaneous lesions are present in about one third of patients. The head, neck and upper trunk are most frequently involved. Typically, patients have a few scattered erosions or tense blisters on a red or urticarial base. However, the extent and number of cutaneous lesions is usually small. On electron ...

Immune Response to DNA and its Role in Causing Lupus In lupus, the immune system is out of balance causing it to produce autoantibodies, or antibodies that target 'self.' The underlying causes of this autoimmune reaction are not well understood. In this video, Dr. David Pisetsky of Duke University Medical Center discusses his research on the immune response to DNA and its role in stimulating lupus disease activity.

Lung Cancer Blood Test - EarlyCDT-Lung Clinical Staff Testimonials Watch as various hospital and clinical staff members discuss using the EarlyCDT-Lung blood test for early lung cancer detection in their offices. See what they think about EarlyCDT technology, the availability of the test, and how useful it has been in their practices For more information, visit ?utm_campaign=Clinical-Staff-Testimonials&utm_source=YouTube Additional information on EarlyCDT-Lung, lung cancer symptoms, risk assessment and other related topics, as well as additional physician testimonials can be found at .

2010 Walk for Lupus Now: Marcy Zitron Chapter Lupus is a chronic, autoimmune disease that can damage any part of the body (skin, joints and/or organs inside the body). Normally our immune system produces proteins called antibodies that protect the body from foreign substances, like bacteria and viruses. With lupus, your immune system cannot tell the difference bet...ween these foreign invaders and your body's healthy tissues and creates autoantibodies ("auto" means "self") to attack and destroy healthy tissue. These autoantibodies cause inflammation, pain, and damage in various parts of the body. On Saturday, May 8, 2010, central Ohio helped the Marcy Zitron Chapter of the Lupus Foundation celebrate it's most successful 'Walk for Lupus Now' yet.

POA?POF?卵巢早老;卵巢早死 POA?POF?卵巢早老;卵巢早死Do etiologies of premature ovarian aging (POA) mimic those of premature ovarian failure (POF)? CONCLUSIONS: Presumed underlying etiologies with POA follow a similar distribution pattern as reported for POF. POA and POF may, therefore, represent a continuum in phenotypical expression of different etiologies of premature ovarian senescence. Like POF, POA should be considered reason to investigate underlying etiologies. Key words: diminished ovarian reserve/premature ovarian failure (POF)/premature ovarian aging (POA)/FMR1 gene/autoimmunity Norbert Gleicher1,2,3,8, Andrea Weghofer1,2,4, Kutluk Oktay1,2,5and David Barad1,2,6,7 A genetic etiology was presumed with 34 triple CGG expansions on the FMR1 gene. An autoimmune etiology was assumed with at least one abnormality in a laboratorypanel, involving antinuclear, antiphospholipid and thyroid antibodies, total immunoglobulin levels and anti-ovarian as well as anti-adrenal autoantibodies. A combined etiology was presumed with both autoimmuneand genetic etiologies, and a patient was considered idiopathic when no abnormalities were found. RESULTS: Twelve of 74 (16.2%) women demonstrated a genetic, 28 (37.8%) an autoimmune, 9 (12.2%) combined and 25 (33.8%) idiopathic etiologiesNorbert Gleicher1,2,3,8, Andrea Weghofer1,2,4, Kutluk Oktay1,2,5and David Barad1,2,6,7 1 Center for Human Reproduction, 21 East 69th Street, New York, NY 10021, USA 2Foundation for Reproductive Medicine, New York, NY, USA 3 ...

Dr John Stanley pt 1 2010 JC Bystryn Pemphigus & Pemphigoid Meeting: From the Bench to the Bedside November 5-6, 2010 in Bethesda MD Pathogenic scFv & V genes from pemphigus vulgaris autoantibodies A copy of the slides can be found at

Frontiers 2007 - Prof Chris Linington - Autoantibodies... Chris Linington is Professor of Immunobiology at the University of Aberdeen. In this interview filmed at the MS Society's Frontiers 2007 research event, he speaks about antibodies which recognise proteins in MS patients and cause damage to nerve fibres.

Effect of Pubertal Hormone Changes on Systemic Lupus Erythematosus Systemic lupus erythematosus (SLE) in childhood usually attacks children as they enter puberty. Hormones change in an orderly pattern during puberty, making the study of lupus in this period of life ideal to understand how hormones affect autoimmunity and disease activity in lupus. Dr. Kathleen O'Neil, Associate Professor of Pediatrics at the University of Oklahoma Health Sciences Center has received a Lupus Foundation of America National Research Program Grant to support a multi-center longitudinal observational study of girls with prepubertal onset SLE as they approach and pass through puberty, measuring hormone levels, autoantibodies and markers of lupus activity. In this video, recorded during the 2010 American College of Rheumatology Annual Scientific Meeting in Atlanta, Georgia, Dr. O'Neil discusses the objectives of the study, how it will be conducted, the potential benefits in our understanding of lupus, and how in the future the disease might be treated and controlled in children.

卵巢早老;卵巢早死 卵巢早老;卵巢早死-POA?POF?卵巢早老;卵巢早死Do etiologies of premature ovarian aging (POA) mimic those of premature ovarian failure (POF)? CONCLUSIONS: Presumed underlying etiologies with POA follow a similar distribution pattern as reported for POF. POA and POF may, therefore, represent a continuum in phenotypical expression of different etiologies of premature ovarian senescence. Like POF, POA should be considered reason to investigate underlying etiologies. Key words: diminished ovarian reserve/premature ovarian failure (POF)/premature ovarian aging (POA)/FMR1 gene/autoimmunity Norbert Gleicher1,2,3,8, Andrea Weghofer1,2,4, Kutluk Oktay1,2,5and David Barad1,2,6,7 A genetic etiology was presumed with 34 triple CGG expansions on the FMR1 gene. An autoimmune etiology was assumed with at least one abnormality in a laboratorypanel, involving antinuclear, antiphospholipid and thyroid antibodies, total immunoglobulin levels and anti-ovarian as well as anti-adrenal autoantibodies. A combined etiology was presumed with both autoimmuneand genetic etiologies, and a patient was considered idiopathic when no abnormalities were found. RESULTS: Twelve of 74 (16.2%) women demonstrated a genetic, 28 (37.8%) an autoimmune, 9 (12.2%) combined and 25 (33.8%) idiopathic etiologiesNorbert Gleicher1,2,3,8, Andrea Weghofer1,2,4, Kutluk Oktay1,2,5and David Barad1,2,6,7 1 Center for Human Reproduction, 21 East 69th Street, New York, NY 10021, USA 2Foundation for Reproductive Medicine, New York ...

Paraneoplastic Pemphigus Dr. Wendy Levinbook, MD discusses Paraneoplastic Pemphigus. See more at PLEASE RATE AND COMMENT!!! Paraneoplastic pemphigus (PNP) typically affects middle-age patients but it can rarely occur in children. There is no racial or ethnic predilection and the incidence is equal in males and females. The most constant clinical feature of this disorder is intractable stomatitis consisting of erosions and ulceration of all surfaces of the oropharynx, including the lips. In fact, this may be the only disease manifestation. Other mucous membranes such as the conjunctival, esophageal, laryngeal, tracheobronchial, nasopharyngeal, oropharyngeal, vaginal, and penile mucosa may be involved. Cutaneous lesions are varied and can include tense bullae resembling bullous pemphigoid, erosions resembling pemphigus vulgaris, target lesions resembling erythema multiforme, lichenoid lesions resembling lichen pl***, or arcuate lesions resembling linear IgA dermatosis. Involvment of the palms and soles with bullae and lichenoid lesions is common and helps to distinguish PNP from other disorders. PNP is associated with either benign or malignant neoplasms in all cases. Non-hodgkin's lymphoma is the most commonly associated tumor. Histopathologic exam demonstrates features of both pemphigus vulgaris and erythema multiforme with suprabasilar acantholysis, basal cell vacuolization, dyskeratotic keratinocytes, and a lichenoid or perivascular mononuclear cell dermal infiltrate. Direct ...

Amy Proal on Antibodies Amy Proal, of Murdoch University. the Autoimmunity Research Foundation, and gave this presentation at the International Congress of Antibodies in Beijing on May 24, 2009. (Amy was affiliated with Georgetown University at the time this presentation was made). The presentation, titled "Antibodies and Infection in the era of the Metagenome" started 10 minutes before lunch, with the lively question and answer period extending 33 minutes into the lunch hour. Amy's blog about the ICA presentation can be found at

rheumachec®: rapid test for early diagnosis of rheumatoid arthritis (RA) The value of the rapid test rheumachec® for diagnosing rheumatism is demonstrated in this training video. The demonstrative educational film gives you some basic information about rheumatoid arthritis (RA), its symptoms, frequency and cause of disease. It also provides some facts and figures about this autoimmune disease, which is the most frequent cause of inflammatory diseases of the joints.

The Autoimmunity Bible & Norton Protocol autoimmunitybible.plus101.com The Autoimmunity Bible & Norton Protocol. 5 Controlled steps for permanent eradication of autoimmunity. This protocol is designed just for people like you if fit any of the 3 categories bellow * You have just been diagnosed and hope that your autoimmune disease will just go away. Sorry, I thought the same but it doesn't work that way. Don't just wait around as this condition takes over your life. * You are not sure you have an autoimmune disorder and you are waiting for a diagnosis. Research have shown that there is a juncture of body chemistry when the chemical imbalance can either results in auto-antibodies formation or much serious conditions, such as cancer. If you address the single most important imbalance none of this will ever happen. * You have been struggling with autoimmunity and have a severe form of the illness and nothing else worked. This is because the true underlying triggers are revealed just recently for the first time and you have never addressed them before. autoimmunity ,the immune system ,disease ,treatment ,immune response ,diseases ,tissues ,theory ,systemic lupus erythematosus ,symptoms ,rheumatoid arthritis ,patients ,mechanisms ,immunological tolerance ,immune system ,women's health ,united states ,type diabetes ,treatments ,tolerance ,tissue ,t-cells ,t cells ,t cell ,syndrome ,skin disease ,search ,scleroderma ,researchers ,research ,related diseases association ,physicians ,pathogenesis ,lymphocytes ,journal of ...

Pemphigus Vulgaris Dr. Wendy Levinbook, MD discusses Pemphigus Vulgaris. See more at PLEASE RATE AND COMMENT!!! Pemphigus vulgaris (PV) is the most common form of pemphigus in North America and Europe. The mean age of onset is 50 to 60 years of age and it affects both ***es equally. It is more common in Jews and in people of Mediterranean descent. Clinically, mucous membranes are always involved. Patients typically present with painful oral mucous membrane erosions although other mucous membranes such as the pharynx, larynx, esophagus, conjunctiva, ***, penis, vagina, and labia may be involved. Cutaneous involvement is variable. The primary lesion is a non-inflamed, flaccid bullae. However, intact bullae are found infrequently because the vesicle roof consists of only a thin portion of epidermis that breaks easily. Therefore, the most common mucocutaneous lesions are erosions subsequent to ruptured bullae. These lesions are typically painful, not pruritic and they are often large, due to their tendency to spread peripherally. Lesions are positive for Nikolsky's sign (lateral pressure of unblistered skin at the periphery of active lesions causes the epidermis to shear off) and for Asboe Hansen's sign (pressure to the top of a bullae causes extension of the blister to adjacent unblistered skin). PV is an intraepidermal autoimmune blistering disorder that occurs secondary to the formation of antibodies that interact with desmoglein 3. This is a 130 kDa transmembrane ...

Dr John Stanley pt 2 2010 JC Bystryn Pemphigus & Pemphigoid Meeting: From the Bench to the Bedside November 5-6, 2010 in Bethesda MD Pathogenic scFv & V genes from pemphigus vulgaris autoantibodies A copy of the slides can be found at

Lung Cancer Blood Test - EarlyCDT-Lung Physician Testimonials Pt. 1 Hear from leading physicians across the United States who have used EarlyCDT-lung as an aid for early lung cancer detection and risk assessment of patients at high risk for lung cancer. For more information, visit ?utm_campaign=Physician-Testimonials-Pt.-1&utm_source=YouTube Additional information on lung cancer symptoms, lung cancer awareness, lung cancer early detection and risk assessment can be found at .

Lung Cancer Blood Test (EarlyCDT-Lung) Case Study - Dr. Kucera Watch Dr. Kucera discuss one of his patients, who took the EarlyCDT-Lung blood test for early lung cancer detection. See what happened after she took the test, and what Dr. Kucera thinks about EarlyCDT technology. For more information, visit ?utm_campaign=Case-Study---Dr.-Kucera-&utm_source=YouTube Additional information on EarlyCDT-Lung, lung cancer symptoms, lung cancer early detection, risk assessment and other related topics, as well as additional physician testimonials can be found at .

Human Genome Sciences Benlysta Drug Approval for Lupus Patients (HGSI) (HGSI) Human Genome Sciences Benlysta Drug Approval for Lupus Patients. New Break through in Human Genome Sciences Benlysta drug approval for lupus patients. Will the Benlysta FDA Approval Come? We believe so at SMF and we will cover the pros and the cons of the HGSI new drug and benefits to humanity. We will take a look at one of the most positive developments in "biotechnology" in the past 50 years. We have highlighted HGSI and the longer term trends relative to the current drug developments. BENLYSTA is an investigational human monoclonal antibody drug. It is the first in a new class of drugs called BLyS-specific inhibitors that recognize and inhibit the biological activity of B-lymphocyte stimulator, or BLyS, which was discovered by HGS in 1996. We and GlaxoSmithKline (GSK) are developing BENLYSTA under a co-development and commercialization agreement entered into in 2006. In lupus, rheumatoid arthritis and certain other autoimmune diseases, elevated levels of BLyS are believed to contribute to the production of autoantibodies -- antibodies that attack and destroy the body's own healthy tissues. BENLYSTA has successfully met its primary endpoint in two pivotal Phase 3 trials in seropositive patients with systemic lupus erythematosus (SLE). In June 2010, HGS and GSK submitted regulatory applications seeking approval to market BENLYSTA in the United States and Europe. The FDA has granted BENLYSTA a priority review designation with a ...

Dr Ye Qian pt 2 2010 JC Bystryn Pemphigus & Pemphigoid Meeting: From the Bench to the Bedside November 5-6, 2010 in Bethesda MD V gene repertoire in pemphigus foliaceus autoantibodies A copy of the slides can be found at